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Here, and consistent with these earlier reports and alike other NPC1 mutant models, 24 h treatment of SH-SY5Y cells with U18666A (2 g/ml) lead to a substantial increase in cholesterol staining intensity in the perinuclear LE/Lys compartment (Fig

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Hassan Biochemistry Department, College of Sciences, King Saud University, Riyadh, Saudi Arabia Abeer Al-Dbass & Ramesa Shafi Bhat Department of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia Laila Al-Ayadhi Autism Research and Treatment Center, Riyadh, Saudi Arabia Laila Al-Ayadhi & Afaf El-Ansary Central Research Laboratory, Female Centre for Scientific and Medical Studies, King Saud University, Riyadh, Saudi Arabia Afaf El-Ansary Authors Wail M