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The distinction between cagrilintide and survodutide matters because it determines receptor interactions, tissue-level effects, and potential combination therapy strategies that a surface-level comparison won't reveal

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These strategies can be envisaged where a TF-BiTE could help redirect endogenous T cells to lyse TF-positive tumor cells and ECs simultaneously, disrupting the tumors blood supply

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Because of the large injection volume necessary, sodium thiosulphate is not suitable for prophylactic use in man