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In the face of persistent oxidative stress and high HOCl levels, methionine sulfoxide can be further oxidized to methionine sulfone (Met-S-O 2 ) [269], a modification that is no longer recoverable by Msr and, therefore, considered irreversible

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

There are few other clear human data on serum GPX3 levels in type 1 diabetes, while there are several reports on type 2 diabetes with other comorbidities [21,22,23], including suggestions that the serum/plasma levels are related to oxidative stress and dependent on the extent of disease progression [24]

The dual role of ROS underscores the need for controlled redox modulation while excessive ROS disrupts healing, physiological levels drive angiogenesis, fibroblast activation, and cell migration

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