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Vascular endothelial growth factor (VEGF), a pro-angiogenic factor secreted by endothelial and tumoral cells, has the prominent role in tumor angiogenesis, growth and metastasis 2,3

Affected individuals have a diminished quality of life secondary to ensuing hoarseness, chest pain and muscle ache

10.1111/apt.14173 [DOI] [PubMed] [Google Scholar] 118

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Bjrkqvist et al., The correlation between plasma and CSF levels of cytokines such as IL-6 and IL-8 suggests that the central and peripheral immune activation in HD are linked