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nDNA Mutations: Patients with nDNA mutations (POLG, TK2) showed a different reaction, thus emphasizing the importance of selecting patients according to their unique genetic profile for all future studies

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Neurotoxicology 1988 ;9(3):391-400

This leads to increased salt and water reabsorption, ultimately causing an expansion in kidney volume (76)

Users on other medications GLP-1 agonists slow gastric emptying, which can affect the absorption of oral medications