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Through integrated transcriptomic and metabolic analyses, we found that NOTCH1 -mutated cells exhibit a distinct bioenergetic profile, characterized by upregulation of mitochondrial programs, enhanced oxidative phosphorylation, and elevated ROS production, all hallmarks of an active mitochondrial phenotype (Figs

It is shown that NOX4 can interact with dynamin-related protein 1 (Drp1) to modulate the activation of the NLRP3 inflammasome (135)

This news came as a shock to the industry, and it's caused a lot of chatter Shared by Christina Farr Until now, no large-scale study has directly compared virtual and in-person pelvic floor physical therapy outcomes

however, we chose to explore an automated approach that used prompting with an LLM to make sense of the data-driven topics and generate plausible themes that could be understood by a human observer instead

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