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Bupropion/Naltrexone Sustained Release (SR) The combined bupropion/naltrexone (NB) therapy induced significantly greater weight loss on a diet and exercise program over 56 weeks compared to monotherapy and placebo (61)

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In the ROC curve analysis shown in Fig

Our data reveal that CPZ exposure not only triggers well-established central pathology but also induces dynamic, temporally coordinated, and region-specific intestinal responses that closely mirror CNS injury and subsequent repair, as summarized in Figure 8