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298 Under excessive ROS levels, ATM triggers downstream sites such as p53 and checkpoint kinase 2 (CHK2) for activation even when the DNA damage response (DDR) is absent, indicating that the activation pathway has no impact on the role of ATM at a certain level, whereas ATM has many other functions independent of the DDR 297 (Table 1, Fig

Raw sequences were processed with Quantitative Insight into Microbial Ecology 2 (QIIME) [24] pipeline using the divisive amplicon denoising algorithm 2 (DADA2) to filter, trim, and merge paired-end reads into amplicon sequence variants (ASVs)

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Updated 2 juni 2025 Vitamin B12 is quite a popular supplement and especially vegans, vegetarians and people who eat little meat