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"Reduction abdominoplasty in patients with massive weight loss." Plastic and Reconstructive Surgery , 129(1), 108-117

The organization also warns that since its not approved for human clinical use by any global regulatory authority, it may lead to negative health effects including immunogenic reactions (antibodies), peptide impurities, and limited safety data for proposed routes of use

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Whether the additive gain seen with cagrilintide+semaglutide replicates against the already-stronger retatrutide is an open empirical question