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& Hutt-Fletcher, L

Blood and Blood Forming system including platelets, blood vessel wall, and bone marrow Cardiovascular system including heart and vascular system Digestive and excretory system including alimentary tract, biliary tract, kidney, liver, pancreas and urinary tract Endocrine system including adrenal gland, kidney, ovary, pituitary gland, renal gland, salivary gland, sebaceous gland, testis, thymus gland and thyroid gland Musclar system including muscles that move the body

It is a critical driver of cancer metastasis that intimately correlates with advanced tumor stage, therapeutic resistance, and poor clinical prognosis (Zhao et al., 2023)