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MSM may be beneficial for skin health by acting as a sulfur donor to keratin

49 Traditional small-molecule antioxidants have failed to alleviate oxidative stress in vivo because of poor brain compatibility, high dosage requirements, and high reactivity, limiting their clinical use

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kurroa rhizome capsules (picrolex) twice daily as a supplement with methoxsalen (a furanocoumarin drug), followed by exposure to light, significantly eliminated the vitiligo patches in 27 of the 30 patients involved in the study ( P kurroa extracts) in activating Nrf2 pathways, leading to the increased expression of detoxifying enzymes (Soni and Grover, 2019)