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With the development of insulin analogs, one important caveat is that insulin concentrations may be falsely low depending on the cross-reactivity with the particular assay used

The 2-NTE has previously been shown to promote phosphorylation of -T172 [114], raising the possibility these putative mTORC1 substrates modulate AMPK activity

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We found that treatment with NAC (500 M) alone had no effect on ROS levels in No AMD cells (Figure 1(a)) but caused a significant decrease in basal ROS content (25%) in AMD ( p = 0.0009) cells compared to no treatment controls (Figure 1(b))

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