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It can serve as a cytoprotective mechanism, promoting resistance, as seen in SCLC where upregulation of lncRNA LYPLAL1-DT enhances autophagy and contributes to multidrug resistance (116)

Mol Psychiatry 28 , 564578 (2023)

From everyday supplements like vitamin D3 and K2 to widely sought-after longevity compounds such as NMN and resveratrol, Sinclairs list is extensive

Research looks at mechanisms such as reducing oxidative stress, modulating growth factors, and impacting extracellular matrix and how all of these connect to gamete quality, implantation, and tissue repair after injury

Mechanistically, RhoA inhibition-induced decrease in ferroptosis and improvement in vascular permeability may be primarily attributed to suppression of oxidative stress and enhancement of mitochondrial function