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To further investigate this relationship and to test the robustness of our correlation results, a bootstrapping-like approach was used, in which 1000 subsets of various sizes (5070 individuals) were randomly drawn from the 71 individuals of the PRESERVE dataset and evaluated based on their Spearman correlation between both the standard and modified MISI and the clamp-based insulin sensitivity

doi: 10.1080/10520290701791839 73 CoteE

By d7, there is a similar ratio of upregulated and downregulated genes