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m , Liver sections from mice fed the standard chow or MASH diet for 12 weeks (n=6) or 24 weeks (n=6) were scored for steatosis, lobular inflammation, hepatocellular ballooning, and NAS, then correlated with the relative abundance of AGXT protein, and ( n ) liver oxalate concentrations

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Other than mRNA, lung spheroid cell Exo loaded with protein cargo showed superior biodistribution and retention in the bronchioles and parenchyma following nebulized administration compared with both HEK cell-derived exosomes and liposomes 217

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This reaction is catalyzed by 5-ALA synthase, located in mitochondria, and is rate limiting in heme synthesis

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