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In contrast, the PDI ALS-mutants (D292N and R300H) lack this redox activity and were not protective against ALS phenotypes, further confirming the importance of the redox activity of PDI in ALS (Parakh et al., 2020)

Under the ionic gelation method, the nanocomposite can cross the BBB via the nasal route and treat CNS diseases[95]

To test this, we propose a minimal feasible, biomarker-enriched, single-arm trial for this patient subset, with co-primary endpoints of safety and objective response rate (ORR)

I dont think so

Convenience of Combination Products Rather than sourcing separate compounds, many researchers prefer peptide blends