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In a cohort of hospitalized Polish patients (vaccinated and unvaccinated), the GSTP1 Ile/Val genotype was associated with a 2.75-fold increased odds of severe COVID-19 among previously vaccinated individuals (p = 0.0398), though no significant link was observed in the unvaccinated group (Orlewska et al., 2023)

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Furthermore, it was shown that cystine starvation rescues the cell death in SLC7A11 high cancer cells under glucose starvation, suggesting that it is cystine import that underlies glucose starvation-induced cell death in SLC7A11 high cancer cells (Goji et al., 2017

doi: 10.1111/cts.12993 53 ColinIMIsaacJDupretPLedantTD'HautcourtJL

Evaluating the treatment effectiveness of Lp-Sav-TL-SN in the mouse model Subsequently, we further evaluated the efficacy of Lp-Sav-TL-SN in treating NPCs in a xenograft mouse model