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Ophthalmology (3rd ed.)

Hung, Chung-Chieh, et al

However, a defining feature of muscle aging is a progressive decline in both the number and functional capacity of MuSCs, which significantly contributes to impaired muscle regeneration and, consequently, to the development of sarcopenia ( Age-related MuSC dysfunction is often characterized by a shift from a reversible quiescent state to an irreversible senescent state (Wang et al., 2025