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Conclusion Glutamine is the most abundant amino acid in plasma, and its metabolism, as a central part of cancer metabolic reprogramming, provides energy support for cancer cells and promotes proliferation, invasion, metastasis, and immune escape

We then conducted association analyses between FRG subtypes and various tumor microenvironment (TME) characteristics, traditional key transcript factor subtypes, clinical features, transcriptional and post-transcriptional regulation, drug response, and the efficacy of immunotherapy

Moreover, APOE4 exhibits a higher binding affinity for Sirt1 when compared with APOE3 and APOE2 (Lima et al

Parkinsonism can be linked to genetics in only a small subset of patients (for a recent review and examples of such conditions, see [7])

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