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(PubMed) Shi Z, Zhen S, Wittert GA, Yuan B, Zuo H, Taylor AW

Upon activation, NLRP3 oligomerizes and recruits ASC via PYD-PYD binding, forming a scaffold that transports procaspase-1 molecules into proximity through the CARD-CARD interaction

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2 Methods We conducted a comprehensive search for existing studies on natural products for the treatment of diminished ovarian reserve and protection of female fertility by modulating PCD