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Unlike full-length human growth hormone, which binds to growth hormone receptors throughout the body and triggers widespread effects, AOD-9604 acts primarily on adipose tissue through a distinct receptor mechanism

Think of it like loosening a stuck jar lidmuch easier than trying to force it off

10.1016/j.mito.2016.04.005 173 SagdicA.SenerO.BulucuF.KaradurmusN.zelH

MS is an autoimmune disease in which reactive T cells interact with antigens presented by macrophages or microglia under pathological conditions, resulting in damage to myelin sheaths and axons and ultimately neuronal loss (244246)

Of note, acidosis alone significantly suppresses peptide synthesis, much like hypoxia 64,65