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Achieving a balance between mucus penetration and cell uptake is still challenging because the neutral, hydrophilic surfaces that benefit mucus penetration can limit interactions with epithelial cells unless they incorporate features such as positive charges or targeting molecules

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Contextualizing the potential clinical impacts of lecanemab, donanemab, and other anti-B-amyloid monoclonal antibodies in early Alzheimer's disease

In this study, the persistent epileptiform spiking and seizures could be due to a significant loss of PVB neurons