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As liquid biopsy technology advances, refining ctDNA-based assays will be crucial in enhancing early detection, disease monitoring, and therapeutic decision making in GBM

10.1046/j.1471-4159.1999.0722334.x 85 JamesS

mentioned that oxidized mtDNA would be cleaved into segments and subsequently transported to the cytoplasm in two steps

Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the ironsulfur cluster scaffold protein (ISCU)

2d), Insr P1195L/ +/ND mice exhibited lower RQ during dark phase compared with WT/ND mice (Fig