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The cell biology of Parkinson's disease

Additionally, if gut permeability is indeed increased in ME/CFS patients, microbes and antigens may be able to cross the epithelial barrier into surrounding tissue and blood, potentially crossing the BBB and altering the HPA axis (443)

A significant limitation of current studies on lactylation is their predominant reliance on mouse models that represent only specific pathological features, which do not fully reflect the actual conditions of patients brains