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Post-microneedling, open micro-channels allow topical brightening serums to penetrate at higher rates

Smith et al., 2010)

Fresh maize leaves (0.5 g) were homogenized in 2.5 mL 0.5 M perchloric acid, incubated on ice for 15 min, and centrifuged at 11,200 g at 4 C for 10 min