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MP also activates the STAT6-STAT3 signaling pathway, inducing the expression of the mucins MUC5AC and MUC5B, thereby downregulating FOXA2, leading to excessive airway mucus secretion, which exacerbates airway infections and is a major cause of mucus obstruction in various chronic airway diseases (132)

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Mnard C, Quirion R, Vigneault E, Bouchard S, Ferland G, Mestikawy E, Gaudreau S, P (2015) Glutamate presynaptic vesicular transporter and postsynaptic receptor levels correlate with Spatial memory status in aging rat models

Among sPLA2 phospholipases, the dominant isoform in keratinocytes, both human (human primary epidermal keratinocytesHPEK) and mouse (murine primary epidermal keratinocytesMPEK), is the sPLA2-IIF isoform