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Compared with healthy controls, patient-derived monocytes showed significantly increased expression of SLC25A33 and pro-inflammatory cytokines, while SLC25A22 and SLC25A37 did not show significant changes in expression (Fig

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These enzymes are alternative respiratory routes, which do not produce energy, but allow viability when the enzymes of the main pathway are affected (Rasmusson et al., 2008, Rasmusson et al., 2009