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Table 2 Genomic DATA 1.5 Polygenic risk scores (PRS) As discussed in previous sections, exome sequencing provides a deeper understanding of the genetic basis of complex disorders, since it enables a global analysis not only of pathogenic variants but also of risk variants, variants of uncertain significance (VUS), and benign variants

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[DOI] [PubMed] [Google Scholar] 51.Shan L., Emanuel R.L., Dewald D., Torday J.S., Asokanathan N., Wada K., Wada E., Sunday M.E

Understanding the precise regulation of the SAM cycle is thus critical not only for basic metabolic processes but also for therapeutic interventions in diseases where methylation imbalances are a key factor

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