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While nearly all this research involves animal models, the consistency of results across different injury types and body systems has generated significant interest in the peptide therapy community

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A specific, transmembrane interface regulates fibroblast activation protein (FAP) homodimerization, trafficking and exopeptidase activity

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For oral administration, clinical trials have studied doses ranging from 1-30 mg daily, with typical protocols using 1-2 mg per dose on an empty stomach