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These interventions include relaxation training, diversion techniques, addressing habit problems (identifying situations that worsen symptoms like scratching and replacing them with healthier responses), and stress management [42,43,44,45,46]

Nrf2 is a critical transcription factor for protection against oxidative stress [107]

Without sufficient blood supply, tissue repair stalls and skin quality deteriorates

These mutations in the GyrA and ParC subunits are situated within the quinolone resistance-determining region (QRDR), specifically close to the active site tyrosines (Tyr122 for GyrA and Tyr120 for ParC) of these enzymes (Ostrer et al., 2019)

50 ml of water in a 150 ml beaker on a heated magnetic stirrer set at approx