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Cyclic AMP-specific and cyclic GMP-specific phosphodiesterase isoenzymes in human cavernous arteriesimmunohistochemical distribution and functional significance

By tagging their protein of interest with GST, researchers can then immobilize it on glutathione agarose beads, and flow over a complex, or simple biochemical mixture to identify interacting proteins

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When determining the Alanine to Lysine ratio as an indirect measure of mitochondrial distress we found that unaffected children had an average ratio of 5.8 and those with konzo have an average ratio of 6.9, both of which are substantially higher than the expected ratio of less than 3 for healthy adolescents (Fig