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At the molecular level, cerebral blood perfusion causes an acute loss of oxygen and glucose, which lowers the generation of adenosine triphosphate (ATP), causes lactic acidosis, and disrupts cellular homeostasis ( in situ small vessel disease, artery-to-artery embolism, and cardioembolic events ( Herbal medicines are being explored as potential neuroprotective agents for ischemic stroke, based on their long history of use in traditional medicine

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