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Illustration of a Protocol-Set Up As an example for the implementation of the steps of the decision diagram, the fm-theta neurofeedback protocol based on Enriquez-Geppert et al

Oral supplementation has become far more effective

The complexity of variant classification is due to (1) that variants of unknown significance are rare in the population and phenotypic information on the specific variants is missing, and (2) that individual variant testing is challenging, costly and slow

(3) observational studies (cohort, case-control, cross-sectional) or experimental/preclinical evidence relevant to NSW-BC pathways

Furthermore, overactivation of glutamate receptors, such as NMDA receptors, raises intracellular Ca2+ levels