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In cases of clinically diagnosed dementia, improvements in neuropsychological test scores are regarded with high face validity and regulatory acceptance, despite their inherent within-subject variability, even among cognitively healthy individuals

PMID: 32917265 Brain Sci AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway

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Various nano-TQ formulations, including nanoemulsions, lipid vesicles, nanostructured lipid carriers, and ethosomes, have been explored to improve solubility, facilitate skin penetration, ensure sustained release, and achieve site-specific targeting