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Why people choose it: Dual-action mechanism for superior appetite and metabolic control Highest weight loss percentages of any approved medication Reduces emotional and mindless eating patterns Improves multiple metabolic risk factors simultaneously Once-weekly injection Common side effects: Similar to semaglutide nausea, diarrhea, constipation, and decreased appetite

Further, co-occurrence of autoimmune atrophic gastritis with other autoimmune conditions, especially autoimmune thyroiditis and type 1 diabetes mellitus, has been reported (11, 12)

For example, a study of MTHFR polymorphism genotypes in colorectal cancer patients reported that the frequency of methylated Bcl-2 promoter was significantly higher in individuals with CC genotype than that of those with CT and TT genotypes, and a significant difference of C and T alleles distribution were observed between patients with methylated and unmethylated Bcl-2 promoter 35

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