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Viral infection may serve as a potential trigger for uveitis

Acknowledgements This study has been funded by JSPS KAKENHI Grants (24K12533 to Sato S, 25K20119 to Tamehisa T, 24K12579 to Tamura I, and 23K27734 to Sugino N) for Scientific Research from the Ministry of Education, Science, and Culture, Japan

The underlying mechanism involves the upregulation of Caspase 3, which induces apoptosis in Leydig and Sertoli cells of the human testis due to excessive ROS generated by heat stress (114, 115) ( Figure 2c )

This was the original target indication based on the animal cognitive enhancement data

Short-term administration of GW501516 improves inflammatory state in white adipose tissue and liver damage in high-fructose-fed mice through modulation of the renin-angiotensin system