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1 In this study, adverse events considered possibly to be caused by hydroxocobalamin were chromaturia (n=5), pink-to-red skin discoloration (n=3), increase in heart rate (n=1), and elevated blood pressure (n=1)

Demonstration of these qualities was realized by several clinical studies both in animals and humans

The split dosing approach maintains more consistent NNMT inhibition throughout the day, potentially enhancing metabolic benefits