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In this case, the deficiency from either of them alone will be better than having both of them, because having both will make the consequences more severe

The consequences of untreated DPN are severe, with the potential progression to neuropathic pain affecting 2033% of patients with DPN and significantly compromising their overall well-being [2, 10]

It typically presents as macrocytic megaloblastic anemia and neurological impairments, including sensory and motor disfunctions, predominantly in the lower extremities, ataxia, and in more advanced stages cognitive decline progressing to dementia, as well as psychiatric disturbances (Sanjay et al., 2022

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However, these findings are still awaiting further confirmation