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It is therefore possible to predict that CXCL9, CXCL10, and CXCL11 may interact with CXCR3-A and activate its downstream signaling cascades, which would then decrease the expression of CXCR3-B at the posttranscriptional or posttranslational level

At the same time, the inferred network reveals the overlap of regulatory genes between NF-B and Nrf2, demonstrating the relationship between NF-B, Nrf2, and hepatotoxicity (Souza et al., 2017)

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Providing research papers documenting mechanisms and outcomes

Tudor M, Jandric I, Marovic A, et al