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doi: 10.1039/d2np00036a 479 ZhangC

Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism

To investigate mechanisms underlying FTLD-GRN, single-cell transcriptomics in the thalamus and frontal cortex of Grn / mice and FTLD-GRN patients identified a conserved astrocytic pathology marked by upregulation of GJA1, AQP4 , and Apoe , and downregulation of the glutamate transporter SLC1A2

doi: 10.1016/j.jep.2023.116945 122 WolfPGDevendranSDodenHLLyLKMooreTTakeiHet al

The simultaneous administration of curcumin and piperine to humans or animals boosted the serum levels by more than a thousandfold (51)