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Ruiz, C

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The heterogeneity in this study was substantial, and we speculate that most of the heterogeneity may have come from clinical sources

However, any curvature that appears during erection is just a symptom of the underlying disease, which is the buildup of plaques and fibrosis in the soft tissue of the penis

Moreover, a relatively small sample size of the subgroup of patients with severe vasculogenic ED might have prevented to capture slightly significant improvements in PSV at dynamic PDU upon l-ARG supplementation, particularly in patients with borderline scores indicating severity, therefore making it challenging to provide conclusive information concerning the potential effect of l-ARG supplementation in patients with borderline severe vasculogenic ED