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Metabolomics allows qualitative and quantitative analysis of all small molecule metabolites in an organism and searches for the relationship between metabolites and physiopathological changes

Biol Trace Element Res (1992) 32:2538

Disruption of Neurotrophic Support: Altered brain-derived neurotrophic factor (BDNF) signaling, compromising neuronal health and synaptic integrity

Glutamates key role in neuronal plasticity suggests it could help remodel the nervous systems in people with ME/CFS

However, it is imperative to state that more oriented studies need to be conducted to understand the role of zinc and other metals in mediating the fibrillation microenvironment of bacterial curl as well as other its effect on other human amyloids