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Mice were continuously fed with assigned diet throughout the remaining 16 weeks of treatment, with weekly monitoring of body weight and blood glucose

KRAS mutant tumors are typically characterized by an immunosuppressive state (106)

Consistent with this observation, PERMANOVA analysis demonstrated no statistically significant difference between pre- and post-intervention metabolomes (F = 0.2135, R = 0.0117, p = 0.857), suggesting that the GF-MKD did not induce large-scale global metabolic remodeling

Nature Reviews Neuroscience , 8 , 5769