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VanLandingham JW, Cutler SM, Virmani S, Hoffman SW, Covey DF, Krishnan K, et al

When released into the synaptic cleft, glutamate activates a family of ligand-gated ion channels called ionotropic receptors (named NMDA, AMPA, and KA)

To assess technical reproducibility and enable cross-tissue normalization, we created a quality control (QC) pool by combining equal amounts of peptide digest from all tissues