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Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma

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In healthy individuals, a recent study reported that androgen deficiency was strongly associated with reduced lean body mass and strength, while estrogen deficiency resulted in an increased proportion of body fat, and both oxandrolone and enobosarm contributed to heightened libido.[35] Currently, enobosarm, a selective androgen receptor modulator with decreased potential for virilization, is under investigation for the treatment of cancer cachexia in a phase III clinical trial.[36] Preliminary unpublished reports suggest improvements in lean body mass with enobosarm