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Why this suits women: Hormonal shifts during perimenopause and menopause redirect fat storage toward the abdominal compartment through declining estrogen, increasing cortisol sensitivity, and reduced growth hormone output

In severe B12 deficiency, methylfolate is trapped in one form and can't be converted to the other folate forms cells need for DNA synthesis and cell division

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DNA synthesis and cell metabolism Intracellular conversion of vitamin B 12 to two active coenzymes, in mitochondria and adenosylcobalamin in the cytoplasm, is necessary for the homeostasis of methylmalonic acid and homocysteine, respectively