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doi: 10.1530/JME-15-0124 263 CarpenterJRJablonskiKAKoncinskyJVarnerMWGyamfi-BannermanCJoss-MooreLAet al

The effect is concentration-dependent and involves recruitment of macrophages, mast cells, and capillary endothelial cells to the wound site (Pickart et al., 2015)

The transport capability of MSNs at the sizes of 20, 40, and 80 nm were evaluated by the authors and were calculated to be 44.0%, 59.2%, and 38.6%, respectively, which were all higher than that of free drugs (32.8%), indicating a size-dependent penetration mechanism