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Development of a gene transfer-based treatment for radiation-induced salivary hypofunction

Sirtuins, particularly SIRT1(Zhao et al., 2022b), are NAD-dependent deacetylases that regulate enzymes involved in fatty acid catabolism, such as AMPK, PPAR-, SREBP-1c, and Nrf2

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In some cases, individuals may develop SIRVA, severe allergic reactions, or other complications linked to pneumococcal bacteria exposure through vaccination