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Real-world US health records show the clinical uptake: the percentage of women with PMOS receiving at least one GLP-1 prescription rose from approximately 2% in 2021 to nearly 18% by 2025

As such the overall impact of the manuscript would benefit greatly by detailed editing and potential re-organization. Response: As per your suggestion, we have replaced the section on requirements and detection of dimers with a reference to the original IUPHAR publication