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The animals treated with melatonin for 18 months showed high levels of APE1 (Apurinic/apyrimidinic endonuclease 1) and OGG1 (8-Oxoguanine glycosylase), two important enzymes involved in the base excision repair pathways of DNA lesions

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(11) Cell wall: Like most pathogenic fungi, the cell wall of Coccidioides immitis is rich in chitin and chitin metabolism is a reasonable target for the design of antifungal agents